Nano and Other Emerging Chemical Technologies Blog

Latest from Nano and Other Emerging Chemical Technologies Blog

On January 11, 2021, the European Commission’s (EC) Scientific Committee on Consumer Safety (SCCS) posted a final opinion entitled Scientific Advice on the Safety of Nanomaterials in Cosmetics.  The EC requested that SCCS determine the nanomaterials, as published in the 2019 catalogue of nanomaterials, for which specific concerns can be identified and justified to establish a priority list of nanomaterials for risk assessment (Article 16(4) Reg. 1223/2009).  The final opinion states that SCCS has identified certain aspects of nanomaterials that constitute a basis for concern over safety to consumers’ health when used in cosmetic products.  These include: Physicochemical aspects…
On January 5, 2021, the National Institute for Occupational Safety and Health (NIOSH) posted a Science Blog item entitled “Understanding the Broad Class of Carbon Nanotubes and Nanofibers (CNT/F) Used or Produced in U.S. Facilities.”  The item summarizes a recently published article in the journal Particle and Fibre Toxicology, “Physicochemical characterization and genotoxicity of the broad class of carbon nanotubes and nanofibers used or produced in U.S. facilities” that addresses whether different-sized CNT/F materials have similar toxicity if inhaled.  For successful commercialization and industrial hygiene, and from a human health perspective, it is important for us…
The American Conference of Governmental Industrial Hygienists (ACGIH®) Threshold Limit Values for Chemical Substances (TLV®-CS) Committee has included carbon nanotubes on its 2021 list of chemical substances and other issues under study.  Being placed on the under study list indicates that the TLV®-CS Committee has selected carbon nanotubes for development of a threshold limit value (TLV®).  ACGIH® describes TLVs® as health-based values representing the opinion of the scientific community that exposure at or below the level of the TLV® does not create an unreasonable risk of disease or injury.  The TLV®-CS Committee seeks substantive data and comments and will…
On January 26, 2021, the Organization for Economic Cooperation and Development (OECD) will hold a webinar on Guidance Document on Aquatic and Sediment Toxicological Testing of Nanomaterials (No. 317).  The webinar will discuss the scope and use of the guidance document, which addresses practical aspects of carrying out valid tests on nanomaterials, and modifications or additions to OECD Test Guidelines procedures intended to improve the accuracy of test results.  Registration for the webinar is open.…
The Organization for Economic Cooperation and Development (OECD) published a report entitled Moving Towards a Safe(r) Innovation Approach (SIA) for More Sustainable Nanomaterials and Nano-enabled Products.  According to the Executive Summary, the report “presents common working descriptions to ensure a common understanding of concepts such as: Safe(r) Innovation Approach and its elements, Safe(r)-by-Design and Regulatory Preparedness.”  The report compiles existing risk assessment tools, frameworks, and initiatives developed for Safe(r)-by-Design.  OECD states that the inventory of risk assessment tools and frameworks should help industry implement a “Safe(r) Innovation Approach” for nanomaterials and nano-enabled products.  This includes a review of lessons…
The Organization for Economic Cooperation and Development (OECD) has posted a report entitled Ability of biopersistent/biodurable manufactured nanomaterials (MNs) to induce lysosomal membrane permeabilization (LMP) as a prediction of their long-term toxic effects.  The report describes “the expanding knowledge on the implications and biological significance of lysosomal and autophagy dysfunction and the subsequent assembly and activation of inflammasome NLRP3 induced by biodurable manufactured nanomaterials.”  According to the report, different types of biodurable nanomaterials are shown to cause LMP, affect autophagy, and cause NLRP3 inflammasome activation.  OECD intends the compilation of available information in the report to contribute to the…
In 2016, the Organization for Economic Cooperation and Development’s (OECD) Working Party on Manufactured Nanomaterials (WPMN) included the Advancing Adverse Outcome Pathway (AOP) Development for Nanomaterial Risk Assessment and Categorization (NanoAOP) project in its program of work.  The objective of the project is to contribute to the future development and application of AOPs for manufactured nanomaterial regulatory decision making by following the principles established by the OECD Extended Advisory Group on Molecular Screening and Toxicogenomics (EAGMST).  OECD has published three reports presenting the outcomes of the project: Advancing Adverse Outcome Pathway (AOP) Development for Nanomaterial Risk Assessment and Categorisation Part
The European Union (EU) Observatory for Nanomaterials (EUON) is conducting a web satisfaction survey.  EUON provides information on the safety, innovation, research, and uses of nanomaterials on the EU market.  It is intended for stakeholders developing policies in the area, consumers, industry representatives, and non-governmental organizations.  EUON is funded by the European Commission (EC) and hosted and maintained by the European Chemicals Agency (ECHA).  Information from the survey will be used to make improvements to the existing website and prioritize areas of development in the future.  The survey should take only five minutes, and responses are completely anonymous.…
On December 1, 2020, the French Agency for Food, Environmental and Occupational Health and Safety (ANSES) announced the results of an assessment of R-Nano, France’s national reporting scheme for substances in nanoparticle form.  In 2013, France began requiring companies that manufacture, import, and/or distribute a “substance with nanoparticle status” in an amount of at least 100 grams per year to submit an annual report with substance identity, quantity, and use information.  The data reported were intended to provide regulatory authorities a better understanding of the nanomaterials placed on the market, enable traceability in the sectors using them, and bring together…
On December 3, 2020, a workshop will be held on “Creating a NanoRisk Governance Council:  Stakeholder evaluation and feedback.”  The workshop is aimed at working with stakeholders to obtain their feedback on the services and on the four scenarios being discussed for the establishment of the proposed NanoRisk Governance Council.  The workshop will comprise a plenary session plus up to four breakout sessions.  Some information about the scenarios will be provided prior to the event.  The workshop is a joint event between projects Gov4Nano, NANORIGO, and RiskGone.…
The European Union (EU) Observatory for Nanomaterials (EUON) announced on November 16, 2020, the results of a study on how citizens perceive nanomaterials and their potential risks to human health and the environment.  According to EUON, the study found that general awareness about the nature, characteristics, and properties of nanomaterials is low.  EUON notes that the level of awareness has increased compared to earlier surveys, however, and is expected to continue increasing in the future.  EUON states that the results confirm that concerns often correlate with a lack of awareness of nanomaterials.  The majority of respondents (87%) indicated that they…
On November 19, 2020, the European Food Safety Authority (EFSA) published a report entitled “Environmental Risk Assessment (ERA) of the application of nanoscience and nanotechnology in the food and feed chain.”  The authors analyzed existing ERA guidance documents for their adequacy to cover issues that are specific for nanomaterials, but note that none of the guidance has a specific focus on the food and feed chain.  Each nanospecific issue was addressed by briefly reviewing the existing methods to address the issue in each separate step of ERA.  The report suggests adaptations necessary in exposure assessment and hazard and…
Registration is now open for the National Nanotechnology Initiative’s (NNI) 2021 NNI Strategic Planning Stakeholder Workshop:  Charting the Path Forward, which will be held January 11-13, 2021.  NNI states that over the past 20 years, it has supported nanotechnology discovery, development, and deployment and has nurtured the strong ecosystem that exists today.  Building on this foundation, nanoscience will underpin a wide range of advanced technologies and enable solutions to challenges into the future.  As NNI enters its third decade, conversations at the January 2021 workshop will identify effective mechanisms to advance research and development, strategies for communication, and priority…
On November 10, 2020, the Senate Committee on Appropriations released 12 fiscal year (FY) 2021 appropriations bills and explanatory statements.  The bill for the Department of the Interior, environment, and related agencies includes funding for the U.S. Environmental Protection Agency (EPA).  The explanatory statement for the bill includes language regarding nanomaterials research at EPA and states: The Committee notes the increased capabilities that the Food and Drug Administration [FDA] has developed to study environment, health, and safety of nanomaterials [nanoEHS] within FDA’s Jefferson Laboratory Campus, including the National Center for Toxicological Research, and its consolidated headquarters at White Oak, Maryland.…
On November 2, 2020, the European Commission (EC) requested a scientific opinion from the Scientific Committee on Consumer Safety (SCCS) on the ultraviolet (UV) filter HAA299 (nano) (chemical name “2-(4-(2-(4-Diethylamino-2 hydroxy-benzoyl)-benzoyl)-piperazine-1-carbonyl)-phenyl)-(4-diethylamino-2-hydroxyphenyl)-methanone”).  According to the EC’s request, the applicant seeks to assess the safety of HAA299 (nano) for use as a UV filter up to a maximum concentration of 10%.  The EC asks SCCS: In light of the data provided, does SCCS consider HAA299 (nano) safe when used as a UV filter in cosmetic products up to a maximum concentration of 10%; In view of the previous SCCS opinion on HAA299…
On November 9, 2020, the European Commission (EC) Scientific Committee on Consumer Safety (SCCS) published two draft opinions for public comment.  In the preliminary opinion on hydroxyapatite (nano), SCCS considered whether the nanomaterial hydroxyapatite is safe when used in leave-on and rinse-off dermal and oral cosmetic products according to the reported maximum concentrations and specifications, taking into account reasonably foreseeable exposure conditions.  SCCS states that having considered the data provided, as well as other relevant information available in the scientific literature, it cannot conclude whether hydroxyapatite composed of rod-shaped nanoparticles for use in oral-care cosmetic products at the maximum…